Sindh Development Society has working experience throughout the Sindh Province. It has implemented the projects almost in all the districts of Sindh. The district was profile of activities implemented is as follows
| S.# | Program / Sector | District | Donor | No of Projects |
| 1 | Human Rights (Women & Children Rights)EVAW End Violence Against Women (WE Can Campaign)EndingTorture in CustodyLegal Education/AssistanceWomen in GovernanceGender JusticeVoter Education Women EmpowermentPeace and Economic Rights | Hyderabad, Thatta, Mitiari, Sukkur, Nosheroferoz, Shikarpur, Dadu, Jamshoro, Khairpur, Jacobabad, Benazir Abad, Tando Mohammad Khan | Unicef SEF Oxfam ESRA-USAID NCHD, Literacy Commission Pakistan | 22 |
| 2 | Education CLCsFormal EducationInformal EducationPost Literacy | Hyderabad, Jamshoro, Kotri- Hyderabad, Shadadkot, Dadu, Tando Allah Yar | UNDP, Oxfam – EC, Trocaire, Aurat Foundation, Madadgar – DFID, Local government, PILER | 8 |
| 3 | Health Family Health Centre Reproductive HealthPrevention of HIV / AidsFamily Welfare Centre | Hyderabad Tando Allah yar | Interact Worldwide-EU Green Star Social Marketing, Family Planning Association of Pakistan, TVO, NATPOW, | 9 |
| 4 | Early Recovery / Emergency Community Infrastructure, LivelihoodTemporary Learning Centers (TLC)Child Friendly Spaces (CFSs)Women Friendly Spaces (WFSs) | Jamshoro, Kotri- Hyderabad, Benazirabad, Khairpur, Sanghar, Nosheroferoz | UNICEF, UNFPA, UNDP, UNESCO-SEF | 8 |
| 5 | WASH / Environment Safe Drinking WaterHygiene Kit DistributionHygiene Practices Environmental Protection | Hyderabad, Tando Allah Yar | OPT-RDT TVO, Oxfam Environment Division Govt of Sindh | 5 |
| 6 | Survey and Research Natioanl Pre ElectionHonor KillingKaro KariNeed assessment | Hyderabad Dadu Interior Sindh UNDP – Local Govt | The Researcher Islamabad , Oxfam, Heinrich Boll Foundation | 4 |